Endocrine Abstracts

Introduction: Cushing’s disease is not likely to be pituitary apoplexy or macroadenoma. We present a case of pituitary apoplexy after dexamethasone suppression test for Cushing’s disease due to macroadenoma.Case report: A 30-year-old man complained of headache and closure of the left upper eyelid. Two years ago he had a headache, and was diagnosed with non-functional macroadenoma of pituitary. In follow, insuppressibly serum levels of cortisol ...

Introduction: Thyroid disorders such as subacute thyroiditis occur rarely in pregnancy. We report a recurrent case of subacute thyroiditis improved with the onset of pregnancy.Case report: A 32-year-old Turkish women who request pregnancy and planned insemination was referred due to malaise and neck pain in the left side a week ago. She was presented with low-grade fever, fatigue, pharingitis symptoms, neck pain and extremely tenderness in the right side...

While low testosterone levels are associated with higher incidence of type 2 diabetes mellitus in males. In contrast, hyperandrogenism is associated with higher risk of type 2 diabetes mellitus in females.We, therefore, have assessed alterations in beta-cell functions before and after testosterone replacement therapy in male patients with idiopathic hypogonadotropic hypogonadism (IHH) and before and after anti-androgen therapy in patients with polycystic...

Introduction: Hypothyroidism is a well-known cause of secondary dyslipidemia, and its link to atherosclerosis has been known for long time. The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) offer important benefits for the large population of individuals at high risk for coronary heart disease. It was aimed to invastigation the relations of the secondary hyperlipidemia included overt and subclinical hypothyroidism and increased serum creatine k...

Introduction: Patients with extremely high triglyceride levels and associated lipemia are at high risk for acute pancreatitis. Hypertryiglycerideamia can be can be provoked when triglyceride levels exceed 1.000 mg/dl of acute pancreatitis.Materials and method: In 7 patients with hyperlipidemic pancreatitis was evaluated. In addition to the standard therapy, they were treated with triglyceride apheresis. Acute pancreatitis was diagnosed based on the prese...

Background: Resistance to thyroid hormone (RTH) is a dominantly inherited syndrome characterized by decreased responsiveness of target tissues to thyroid hormone. Two members of a Turkish family, a mother and son, had thyroid function tests suggestive of resistance to thyroid hormone (RTH).Methods: The clinical presentation was, however, different. The mother (proposita) had palpitation, weakness, tiredness, nervousness, dry mouth and was misdiagnosed as...

Human chorionic gonadotropin bears structural homology to pituitary thyrotropin. The extremely elevated levels of human chorionic gonadotropin in patients with molar pregnancy or other trophoblastic diseases can lead to hyperthyroidism. We describe a patient with molar pregnancy who had secondary hyperthyroidism prepared rapidly by plasmapheresis for surgery. After first plasmapheresis the clinical picture improved dramatically. Three subsequent plasmapheresis provided a 75.1%...

Pheochromocytomas are tumors capable of producing catecholamines and a variety of biologically active resulting in unusual clinical manifestations. We report the case of 18-year-old female with pheochromocytoma exhibiting fever of unknown origin. She had experienced continuous fever (ranging between 37.1–41  °C) and chills for previous several weeks. Antipyretics had been ineffective in lowering the body temperature and she was referred to our hospital when an a...

Parathyroidectomy for hyperparathyroidism can be complicated with development of Hungry Bone Syndrome (HBS), a constellation of profound hypocalcemia with hypomagnesemia and hypophosphatemia. The severity of this potential life-threatening condition is related to the extent of the parathyroid-mediated high-turnover bone disease. We present a case of a 59-year-old woman developing post-surgical HBS as a result of longstanding severe unrecognized primary hyperparathyroidism (PHP...

Polymorphisms in the Angiotensin-converting enzyme (ACE) gene have been associated with development of diabetic nephropathy (DN), a major microvascular complication of the type 2 diabetes mellitus (T2DM). Since the genetic predisposition plays an important role in development of DN in patients with T2DM, genetic testing might largely contribute to better assessment of the risk of DN in such patients. The aim of this study is to investigate the association of the ACE gene I/D p...